Duane Allman played this guitar on ‘Layla.’ Now it’s heading to the big stage.

Duane Allman’s Goldtop guitar that he played on the hit song “Layla” will be traveling to Madison Square Garden in March for a tribute concert to The Allman Brothers Band.

Richard Brent, executive director of The Allman Brothers Band Museum said the guitar will travel from its home at The Big House to New York City.

“It’s played on so many great songs, and there’s tons of photos of Duane playing it,” he said. “Getting it out and letting people play it not only promotes the museum but more importantly keeps Duane Allman’s name and legacy out there and alive and well.”

The Brothers — Celebrating 50 Years of the music of The Allman Brothers Band performance will be held March 10 with the current band members: Jai Johanny “Jaimoe” Johanson, who was an original member, along with Warren Haynes, Derek Trucks, Oteil Burbridge and Marc Quinones, according to The Brothers’ website.

Duane Allman played the guitar, named “Layla,” on the first two Allman Brothers records, self-titled “The Allman Brothers Band” and “Idlewild South.”

Allman played the guitar on the song “Layla” with Derek and the Dominos, featuring rock guitar legend Eric Clapton. Allman can be heard playing the slide guitar at the end of the recording.

Later, Allman traded his 1957 Gibson Les Paul to Rick Stine for a cherry sunburst Gibson Les Paul after Stine’s band, The Stone Balloon, opened for the Allman Brothers Band at a concert in Daytona on Sept. 16, 1970.

The guitar had a hard life until Scott Lamar rescued the guitar in 1977, when he bought it from Coastal Discount Music for $475, Brent said.

“Layla” was refinished three times, and it sold for a record-breaking $1.25 million July 21, 2019.

The new owner of the guitar made an agreement with the museum so the museum can have the guitar on display for six months out of the year, Brent said.

The last time the guitar traveled to Madison Square Garden was for the Crossroads Guitar Festival in 2014, and Clapton and Derek Trucks played the guitar, Brent said.

He said Trucks always loves to play this particular guitar, and it is amazing to watch different artists play it.

“We hate to see wonderful instruments, great guitars that still have so much to say, just stuck behind glass,” Brent said. “We want to hear the guitar because it truly is an amazing instrument with its own voice.”