The Atlanta Falcons take over the Thursday night spotlight in the NFL with a home game against NFC South rival Tampa Bay.
Westside and rival Central meet for the 13th time, with Westside winning the previous 12 games.
Houston County and Warner Robins face off at McConnell-Talbert Stadium; the Demons own a 12-3-1 record in the series.
Northside is 5-0 all-time against region foe Jones County as the two teams meet in Region 2-AAAAA action.
Georgia Tech opens ACC play at Virginia Tech in a game that typically is key in the Coastal Division race.
Georgia Southern’s first Sun Belt game will be played in Mobile, Alabama, against South Alabama.
Sept. 18 HIGH SCHOOL: Southwest at JordanNFL: Tampa Bay Buccaneers at Atlanta Falcons
HIGH SCHOOL: Central vs. Westside; Northeast at Shaw; Rutland at Kendrick; Baldwin at Thomasville; Bleckley County at Dublin; Gatewood at Brentwood; CFCA at Thomas Jefferson; Crawford County at Chattahoochee County; Crisp County at Dougherty ; Dodge County at Southeast Bulloch; Dooly County at Talbot County; Stewart County at East Laurens; FPD at GMC; Tattnall Square at Hancock Central; Hawkinsville at Brookstone; Houston County vs. Warner Robins; Long County at Jeff Davis; Creekside at John Hancock; Piedmont at John Milledge; Johnson County at Calvary Day; Northside at Jones County; Lamar County at Ola; Fitzgerald at Macon County LaGrange at Mary Persons; Montgomery County at Savannah Country Day; Morgan County at Monticello; Strong Rock Christian at Mount de Sales; Spencer at Peach County; Perry at Brooks County; Putnam County at Social Circle; Stratford at Aquinas; Schley County at Taylor County; Telfair County at Turner County; Robert Toombs at Trinity Christian; Veterans at Valdosta; McIntosh County Institute at Vidalia; Washington County at Burke County; Wilcox County at Lanier County; David Emanuel at Windsor; Northside-Columbus at Upson-Lee; Warren County at Wilkinson County; Treutlen at Savannah Christian; Robert Morris at Crisp Academy; Lincoln County at Twiggs County; Wheeler County at Jenkins County
COLLEGE: Troy at Georgia; Georgia Tech at Virginia Tech; Ave Maria at Mercer; Georgia Southern at South Alabama; Georgia State at Washington; Clark Atlanta at Fort Valley State; Delta State at Valdosta State; Johnson C. Smith at West Georgia; Morehouse vs. Central State in Chicago; Lane at Paine; Shorter at West Texas A&M; Middle Georgia State at GMC